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Scanners

OS-FLi™
Fluorescence +
Brightfield

Dual Imaging — One Scanner

The only OptraSCAN scanner with both fluorescence and brightfield imaging. Designed for research and clinical workflows that require FISH, multiplex IF, and traditional histology — all in a single platform.

80–480
Slide Capacity
2
Imaging Modes
<2min
Scan at 40×
FISH
+ Multiplex IF
Applications

Two imaging modes.
Unlimited applications.

From FISH analysis to traditional histology — the OS-FLi handles both fluorescence and brightfield workflows without switching instruments.

Fluorescence

FISH Analysis

Detect chromosomal abnormalities, gene amplifications, and translocations on FISH-stained specimens with high-resolution fluorescence imaging.

Fluorescence

Multiplex IF

Multi-channel fluorescence imaging for complex biomarker co-localization studies and tumor microenvironment analysis.

Brightfield

Histopathology

Traditional H&E and IHC imaging for routine diagnostic workflows. Full compatibility with all brightfield staining protocols.

Research

Biomedical Research

High-throughput fluorescence imaging of labeled cells, tissues, and biomolecules for cell biology, immunology, and neuroscience studies.

Research

Drug Discovery

High-content screening for evaluating drug candidate effects on cellular morphology. Dual modes facilitate biomarker discovery and validation.

Clinical

IHC Quantification

Scan and quantify fluorescently labeled tissue sections to assess protein expression levels and localization with precision.

Technical Specifications

Full specs at a glance.

SpecificationDetail
Imaging ModesBrightfield + Fluorescence
Slide Capacity80 / 160 / 240 / 320 / 400 / 480 configurations
Scan Time (15×15mm)<2 min at 40×
Slide Formats1×3″, 2×3″, 3×3″, 4×3″
Magnification20×, 40×
Image OutputJPEG2000, TIFF, oTIFF, DICOM
Weight233.6 lbs (106 kg)
DimensionsW: 24.2″, L: 37.4″, H: 24.8″
Fluorescence WorkflowsFISH, multiplex IF
Tissue SamplesCytology, histology, hematology, special stains; fluorescence including FISH and multiplex IF, sputum
AI / SoftwareFully compatible with OptraSCAN IMS & AI analytics
Also Available

Explore our other
scanner models.

OS-SiX™
6-Slide Brightfield
OS-Lite™
15-Slide Brightfield
OS-Ultra™
80–480-Slide Brightfield

Unlock fluorescence
with OS-FLi.

See how dual-mode imaging can expand your lab's capabilities — from FISH and multiplex IF to traditional histology, all in one scanner.

Request a Demo
FAQ

Questions,
answered.

What labs most often ask us about digital pathology, our scanners, and how to get started.

Does the OS-FLi scan both fluorescence and brightfield slides?

Yes. It is OptraSCAN's only dual-mode scanner, handling FISH and multiplex IF alongside H&E and IHC brightfield slides.

What fluorescence applications does the OS-FLi support?

FISH for chromosomal abnormalities and gene amplification, multiplex IF for biomarker co-localization, and fluorescent IHC quantification.

How many fluorescence channels and which filter sets does the OS-FLi support?

OptraSCAN has 7 filter slots, so you can choose whichever filters your lab uses regularly. OptraSCAN supports all the standard FL filters.

How fast does the OS-FLi scan?

Under 2 minutes at 40× for a 15×15 mm area.

What slide capacity does the OS-FLi offer?

80 to 480 slides, in the same configurations as the OS-Ultra.

Is the OS-FLi suited to drug discovery research?

Yes. It supports high-content screening and biomarker discovery and validation using both imaging modes.