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Analytics — Prostate Cancer

AI-Powered Gleason Grading
& Biomarker Analysis

A deep learning algorithm that automates Gleason grading on H&E-stained prostate tissue — delivering objective, reproducible scores to advance prostate cancer research.

The Algorithm

Deep learning meets
Gleason grading.

OptraSCAN's Prostate Cancer Algorithm applies advanced deep learning to high-resolution H&E-stained whole-slide images, recognizing patterns in tumor architecture and cell morphology to deliver consistent, objective Gleason grades.

Beyond grading, the platform enables precise analysis of biomarkers relevant to prostate cancer — offering critical insights into tumor aggressiveness and potential response to treatment.

Gleason Grading H&E Staining Deep Learning Tumor Architecture Biomarker Analysis Automated Scoring
Gleason Grade Classification

Automated scoring across the full Gleason spectrum.

1/5
Well-differentiated
small, uniform glands
2/5
Loosely packed
irregular glands
3/5
Infiltrative glands
with variable size
4/5
Fused, cribriform
or poorly defined
5/5
No glandular
differentiation
How It Works

From H&E slide to Gleason score
in four steps.

01

Image Acquisition

High-resolution whole-slide images are captured using OptraSCAN scanners, preserving the cellular detail needed for accurate architectural and morphological analysis at 20× or 40×.

02

Preprocessing & Quality Control

Images undergo automated preprocessing to ensure optimal quality. A region adequacy check confirms tissue suitability before analysis proceeds.

03

Deep Learning Analysis

The algorithm performs Gleason grading by recognizing patterns in tumor architecture and cell morphology — classifying tissue regions and assigning grades across the full Gleason spectrum.

04

Scoring & Reporting

Detailed Gleason scores, grade group assignments, and biomarker analysis reports are generated automatically — ready for documentation, review, or further analysis.

Key Capabilities

Built for reproducible
prostate cancer research.

Automated Gleason Grading

Deep learning analyzes H&E-stained whole-slide images to deliver consistent, objective Gleason grades — reducing inter-reader variability and enhancing prognostic accuracy across studies.

Biomarker Evaluation

Precise analysis of biomarkers relevant to prostate cancer, offering critical insights into tumor aggressiveness and potential response to treatment protocols.

Efficiency & Consistency

Automated evaluation reduces time and variability associated with manual Gleason grading — delivering reproducible results with significantly reduced workflow burden.

Comprehensive Reporting

Integrated reporting module streamlines case management and documentation. Structured outputs are ready for publication, review, or downstream computational analysis.

Benefits

Why researchers choose OptraSCAN
for prostate cancer analysis.

Enhanced Accuracy

AI-driven Gleason grading and biomarker analysis improve reliability and precision, supporting consistent results across cases, readers, and research sites.

Faster Turnaround

Automated analysis accelerates prostate cancer evaluations, freeing researchers to focus on interpretation and high-level clinical decisions.

Reproducible Results

The algorithm minimizes subjective variability, ensuring reliable Gleason grading and biomarker assessment that holds up across independent reviews.

Research & Validation

Rigorously validated.
Continuously refined.

OptraSCAN's Prostate Cancer Algorithm is validated through collaborations with leading institutions and clinical experts. Our ongoing research ensures the algorithm meets the highest standards in accuracy, consistency, and applicability — with continuous improvements driven by the latest scientific findings.

The algorithm is built on the same research foundation that earned recognition from the Government of India — validated across 9 hospital sites and 10,000+ patient datasets.

9
Hospital validation sites
10K+
Patient dataset
DBT
Government certified
AI
Deep learning architecture
Compatible Scanners

Works with every
OptraSCAN system.

OS-SiX™
6-Slide Brightfield
OS-Lite™
15-Slide Brightfield
OS-Ultra™
80–480 Slide Brightfield
OS-FLi™
Fluorescence + Brightfield

Advance prostate cancer research with OptraSCAN.

See how automated Gleason grading and biomarker analysis can bring objectivity and speed to your prostate cancer research workflow.

Request a Demo