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CytoSiA™ by OptraSCAN

Scale Cervical Cancer
Screening. No Extra Staff.

A complete digital cytology solution combining brightfield scanning, AI-powered triage, and automated reporting — making cervical cancer screening faster, more consistent, and accessible at any scale.

Bethesda Classification
AI-Powered Triage
Slide-to-Report in Minutes
Mobile & Cloud-Ready
Powered by OS-SiA™
Complete Digital Cytology Solution

One platform. Slide to structured report in minutes.

CytoSiA combines brightfield slide scanning, AI-powered cell classification, and automated Bethesda-standardized reporting into a single workflow — helping labs deliver faster, more consistent cervical cancer screening without adding staff or infrastructure.

Scan Any Volume

Works with OS-SiX (6 slides) through OS-Ultra (480 slides). Z-stacking, AI autofocus, and composite imaging built in.

AI Triage & Classification

Flags normal cases, identifies HSIL, LSIL, ASCUS, ASC-H, SCC, and AGC — ranking atypical cells by probability for focused review.

Automated Reports

Clinician-ready reports with thumbnails, classification stats, and flagged regions. Full EMR/LIS integration available.

Deploy Anywhere

Mobile-ready and cloud-connected. From national labs to mobile screening units in underserved communities.

How CytoSiA Works

Scan. Index. Analyze.
Slide to report in minutes.

A seamless digital workflow from prepared slide to clinician-ready report — powered by OS-SiA™, the world's first patented technology that scans, indexes, and analyzes simultaneously.

01
Scan
Digitize cervical cytology slides using OptraSCAN's OS-SiX, OS-Lite, or OS-Ultra brightfield scanners with Z-stacking, AI autofocus, and proprietary composite imaging. Customizable for third-party scanners or existing digital images.
02
Index
IMAGEPath® automatically indexes all scanned slides — generating thumbnails, metadata, and navigational maps. CytoSiA simultaneously runs AI to flag Bethesda-classified abnormalities in real time, organizing cases by status for rapid access.
03
Analyze
AI classifies individual cells (HSIL, LSIL, ASCUS, ASC-H, SCC, and AGC), ranking atypical cells by probability. Structured, clinician-ready reports are generated with thumbnails, classification stats, and flagged regions. Full EMR/LIS integration available.
AI Cell Classification

Probability-ranked results.
Clinician-ready reports.

CytoSiA's AI engine classifies individual cervical cells according to the Bethesda system, ranking each by probability of abnormality. Pathologists see the most critical findings first — reducing review time, fatigue, and missed detections.

Reports are generated automatically with visual summaries, classification statistics, and flagged regions — ready for clinical review or EMR/LIS integration.

What Makes CytoSiA Different

Built to scale screening
without scaling cost.

Unlike traditional digital cytology tools, CytoSiA is designed from the ground up for scalability, accessibility, and real-world deployment — from national programs to mobile outreach clinics.

AI-First Triage

Flags high-confidence normal cases automatically, freeing pathologists to focus on atypical and borderline results.

Probability Ranking

Atypical cells ranked by AI confidence — the most suspicious findings surface first for immediate attention.

No Vendor Lock-In

Optimized for OptraSCAN scanners but customizable for third-party systems and existing digital images.

Mobile & Cloud-Ready

Extend screening into underserved communities with cloud-connected, telepathology-enabled mobile deployment.

Trained on Millions

Deep learning models trained on millions of cervical cancer datasets for high sensitivity and specificity.

Automated Reporting

Structured, clinician-ready reports with Bethesda classification, visual summaries, and EMR/LIS integration.

Supporting the WHO Elimination Strategy

Cervical cancer can be eliminated —
if labs go digital.

The WHO has set ambitious 90-70-90 elimination targets by 2030. CytoSiA helps screening programs close the gap between where they are and where they need to be.

90%
HPV vaccination coverage for girls by age 15
70%
Screening with high-performance test by ages 35 and 45
90%
Treatment rates for pre-cancer and invasive cervical disease
6–480
Slide capacity across OptraSCAN scanner range
AI
Autofocus + Z-stacking + composite imaging
EMR
Full EMR/LIS integration for structured reporting
24/7
Global technical support and training
Use Cases

Where CytoSiA delivers
the most impact.

Purpose-built for the settings driving cervical cancer elimination — from national screening infrastructure to last-mile mobile units.

National Screening Programs

Scale cervical cancer screening to reach millions of women with consistent, standardized AI-assisted triage and automated reporting across the entire program.

Public Health Labs in LMICs

Fast, cost-effective triage for low- and middle-income countries where trained cytotechnologists are scarce and screening demand is highest.

Diagnostic Cytology Labs

Mid- to high-volume labs improving throughput and consistency. Reduce reader fatigue and missed detections while maintaining clinical quality.

Mobile Screening & NGOs

Telepathology-ready mobile deployment extending screening into underserved communities. Cloud-connected for remote expert review and collaboration.

Compatible Scanners

Works with every
OptraSCAN system.

OS-SiX™
6-Slide Brightfield
OS-Lite™
15-Slide Brightfield
OS-Ultra™
80–480 Slide Brightfield
OS-FLi™
Fluorescence + Brightfield

Scale screening with CytoSiA.

See how AI-powered digital cytology can transform your cervical cancer screening program — from slide to structured report in minutes, at any scale.