Whole Slide Imaging (WSI) involves digitally scanning tissue slides with thin sections of specimens for microscopic examination, storing the images as high-resolution digital files. This technology facilitates remote collaboration and analysis, emphasizing image quality, ease of use, and speed.
The WSI process begins with selecting an appropriate scanner and microscope. Once chosen, slides are prepared according to standard protocols. These slides are then placed on the scanner’s stage and scanned using a motorized platform that moves across the surface at varying speeds, depending on the required resolution. The collected image data is processed using advanced algorithms to create a digital version of the specimen, which can be stored in a database. These digital images can be accessed by colleagues for further analysis and collaboration.
WSI allows researchers to review slides remotely without the need for physical handling, making the process more convenient and cost-efficient. Additionally, WSIs do not require special reagents or consumables for preparation, further reducing costs.
Researchers can obtain objective measurements from images like size distributions, cell counts, cellular patterns, and staining methods with the help of whole-slide imaging.
Digital versions of slides stored in databases enable worldwide collaboration, allowing institutions to access and analyze slides from anywhere with an internet connection.
WSI technology accelerates the analysis of glass slides, creating digital images that can be stored and shared electronically. Automated image analysis using AI can free up research staff, and the scalability of WSI allows for rapid expansion without additional physical resources. Centralized datasets save space and provide easier access to information, with features like teleconferencing facilitating global collaboration.
The whole slide scanner offers high-resolution imaging of tissue samples, facilitating the observation and analysis of molecular changes at a microscopic level. Digitizing tissue samples with WSI allows remote access to top-notch images, promoting collaborative research regardless of physical location. The emergence of digital pathology and WSI signifies profound changes in life sciences. In essence, WSI marks a significant advancement in research technology, holding vast potential for enhancing research and development processes in pharmaceutical and biotech industries.
Tissue biobanking institutions receive hundreds and thousands of individual slides through a whole slide scanner which can help in studying diseases or treatments without needing additional physical specimens or costly lab equipment. Unlike traditional glass slides, these are easier to distribute among different research groups offering better protection against factors like dust and humidity that could interfere with their quality over time. Moreover, they offer detailed insights into subcellular alterations, aiding in the creation of potentially more effective drugs or therapies.
Whole Slide Imaging technology is increasingly adopted in pathology for streamlined and remote collaboration among researchers. As it progresses, it's poised to make substantial contributions to life sciences and research. Future enhancements may prioritize improving image resolution and accuracy. Developers are also investigating the integration of artificial intelligence and machine learning to aid in image analysis. To learn about digital pathology and advancing technologies for research in life sciences, read more on our website today.